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Strategies to Extend Thrombolytic Time Window for Ischemic Stroke Treatment: An Unmet Clinical Need

To date, reperfusion with tissue plasminogen activator (tPA) remains the gold standard treatment for ischemic stroke. However, when tPA is given beyond 4.5 hours of stroke onset, deleterious effects of the drug ensue, especially, hemorrhagic transformation (HT), which causes the most significant mor...

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Détails bibliographiques
Publié dans:J Stroke
Auteurs principaux: Peña, Ike dela, Borlongan, Cesar, Shen, Guofang, Davis, Willie
Format: Artigo
Langue:Inglês
Publié: Korean Stroke Society 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307939/
https://ncbi.nlm.nih.gov/pubmed/28178410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5853/jos.2016.01515
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