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A High-Content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-Like Kinase 1

Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults and there are few effective treatments. GBMs contain cells with molecular and cellular characteristics of neural stem cells that drive tumour growth. Here we compare responses of human glioblastoma-derived neural stem (G...

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Détails bibliographiques
Auteurs principaux: Danovi, Davide, Folarin, Amos, Gogolok, Sabine, Ender, Christine, Elbatsh, Ahmed M. O., Engström, Pär G., Stricker, Stefan H., Gagrica, Sladjana, Georgian, Ana, Yu, Ding, U, Kin Pong, Harvey, Kevin J., Ferretti, Patrizia, Paddison, Patrick J., Preston, Jane E., Abbott, N. Joan, Bertone, Paul, Smith, Austin, Pollard, Steven M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813721/
https://ncbi.nlm.nih.gov/pubmed/24204733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077053
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