A High-Content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-Like Kinase 1

Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults and there are few effective treatments. GBMs contain cells with molecular and cellular characteristics of neural stem cells that drive tumour growth. Here we compare responses of human glioblastoma-derived neural stem (G...

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Detalhes bibliográficos
Main Authors: Danovi, Davide, Folarin, Amos, Gogolok, Sabine, Ender, Christine, Elbatsh, Ahmed M. O., Engström, Pär G., Stricker, Stefan H., Gagrica, Sladjana, Georgian, Ana, Yu, Ding, U, Kin Pong, Harvey, Kevin J., Ferretti, Patrizia, Paddison, Patrick J., Preston, Jane E., Abbott, N. Joan, Bertone, Paul, Smith, Austin, Pollard, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813721/
https://ncbi.nlm.nih.gov/pubmed/24204733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077053
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