A Pilot Study Using Next-Generation Sequencing in Advanced Cancers: Feasibility and Challenges

PURPOSE: New anticancer agents that target a single cell surface receptor, up-regulated or amplified gene product, or mutated gene, have met with some success in treating advanced cancers. However, patients' tumors still eventually progress on these therapies. If it were possible to identify a...

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Autores principales: Weiss, Glen J., Liang, Winnie S., Demeure, Michael J., Kiefer, Jeff A., Hostetter, Galen, Izatt, Tyler, Sinari, Shripad, Christoforides, Alexis, Aldrich, Jessica, Kurdoglu, Ahmet, Phillips, Lori, Benson, Hollie, Reiman, Rebecca, Baker, Angela, Marsh, Vickie, Von Hoff, Daniel D., Carpten, John D., Craig, David W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813699/
https://ncbi.nlm.nih.gov/pubmed/24204627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076438
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