A Pilot Study Using Next-Generation Sequencing in Advanced Cancers: Feasibility and Challenges

PURPOSE: New anticancer agents that target a single cell surface receptor, up-regulated or amplified gene product, or mutated gene, have met with some success in treating advanced cancers. However, patients' tumors still eventually progress on these therapies. If it were possible to identify a...

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Hlavní autoři: Weiss, Glen J., Liang, Winnie S., Demeure, Michael J., Kiefer, Jeff A., Hostetter, Galen, Izatt, Tyler, Sinari, Shripad, Christoforides, Alexis, Aldrich, Jessica, Kurdoglu, Ahmet, Phillips, Lori, Benson, Hollie, Reiman, Rebecca, Baker, Angela, Marsh, Vickie, Von Hoff, Daniel D., Carpten, John D., Craig, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813699/
https://ncbi.nlm.nih.gov/pubmed/24204627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076438
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