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Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95
Although histone H3 lysine 4 (H3K4) methylation is widely associated with gene activation, direct evidence for its causal role in transcription, through specific MLL family members, is scarce. Here we have purified a human MLL2 (Kmt2b) complex that is highly active in H3K4 methylation and chromatin...
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Główni autorzy: | , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
2013
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3813012/ https://ncbi.nlm.nih.gov/pubmed/23995757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2656 |
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