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Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis
It remains unknown if biophysical or material properties of biomolecular condensates regulate cancer. Here we show that AKAP95, a nuclear protein that regulates transcription and RNA splicing, plays an important role in tumorigenesis by supporting cancer cell growth and suppressing oncogene-induced...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7425812/ https://ncbi.nlm.nih.gov/pubmed/32719551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0550-8 |
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