A targeted DNA vaccine encoding Fas ligand defines its dual role in the regulation of experimental autoimmune encephalomyelitis

This study used naked DNA vaccination to induce breakdown of tolerance to self and thus elicit immunological memory to native, membrane-bound Fas ligand (FasL). Upon induction of experimental autoimmune encephalomyelitis (EAE), this memory was turned on to provide protective immunity. FasL-specific...

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Bibliographic Details
Main Authors: Wildbaum, Gizi, Westermann, Juergen, Maor, Gila, Karin, Nathan
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC381283/
https://ncbi.nlm.nih.gov/pubmed/10974020
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