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C-C chemokine–encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis

Depending on the method of immunization, a single administration of CFA may result in the development of a local inflammatory process or chronic polyadjuvant-induced arthritis (AA). We administered naked DNA vaccines encoding MIP-1α, MCP-1, MIP-1β, and RANTES to Lewis rats and confirmed that each of...

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Detalhes bibliográficos
Main Authors: Youssef, Sawsan, Maor, Gila, Wildbaum, Gizi, Grabie, Nir, Gour-Lavie, Alumit, Karin, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314324/
https://ncbi.nlm.nih.gov/pubmed/10930439
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