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Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling

The chromatin regulatory factor SIRT6 plays pivotal roles in metabolism, tumor suppression, and aging biology. Despite the fundamental roles of SIRT6 in physiology and disease, only a handful of molecular and functional interactions of SIRT6 have been reported. Here, we characterize the SIRT6 intera...

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Detalhes bibliográficos
Main Authors: Simeoni, Federica, Tasselli, Luisa, Tanaka, Shinji, Villanova, Lidia, Hayashi, Mayumi, Kubota, Kazuishi, Isono, Fujio, Garcia, Benjamin A., Michishita-Kioi, Eriko, Chua, Katrin F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812651/
https://ncbi.nlm.nih.gov/pubmed/24169447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03085
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