STRUCTURAL VARIATION GOVERNS SUBSTRATE SPECIFICITY FOR ORGANIC ANION TRANSPORTERS (OAT) HOMOLOGS: POTENTIAL REMOTE SENSING BY OAT FAMILY MEMBERS

Organic Anion Transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding preferences and transport function of olf...

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Hlavní autoři: Kaler, Gregory, Truong, David M., Khandelwal, Akash, Nagle, Megha, Eraly, Satish A., Swaan, Peter W., Nigam, Sanjay K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812435/
https://ncbi.nlm.nih.gov/pubmed/17553798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703467200
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