STRUCTURAL VARIATION GOVERNS SUBSTRATE SPECIFICITY FOR ORGANIC ANION TRANSPORTERS (OAT) HOMOLOGS: POTENTIAL REMOTE SENSING BY OAT FAMILY MEMBERS

Organic Anion Transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding preferences and transport function of olf...

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Detaylı Bibliyografya
Asıl Yazarlar: Kaler, Gregory, Truong, David M., Khandelwal, Akash, Nagle, Megha, Eraly, Satish A., Swaan, Peter W., Nigam, Sanjay K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812435/
https://ncbi.nlm.nih.gov/pubmed/17553798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703467200
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