Three-Dimensional Structure of CAP-Gly Domain of Mammalian Dynactin Determined by Magic Angle Spinning NMR Spectroscopy: Conformational Plasticity and Interactions with End Binding Protein EB1

Microtubules (MTs) and their associated proteins (MAPs) play important roles in vesicle and organelle transport, cell motility and cell division. Perturbation of these processes by mutation typically gives rise to severe pathological conditions. In our efforts to obtain atomic information on MAP/MT...

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Bibliografiske detaljer
Main Authors: Yan, Si, Hou, Guangjin, Schwieters, Charles D., Ahmed, Shubbir, Williams, John C., Polenova, Tatyana
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812427/
https://ncbi.nlm.nih.gov/pubmed/23648839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.027
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