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Three-Dimensional Structure of CAP-Gly Domain of Mammalian Dynactin Determined by Magic Angle Spinning NMR Spectroscopy: Conformational Plasticity and Interactions with End Binding Protein EB1

Microtubules (MTs) and their associated proteins (MAPs) play important roles in vesicle and organelle transport, cell motility and cell division. Perturbation of these processes by mutation typically gives rise to severe pathological conditions. In our efforts to obtain atomic information on MAP/MT...

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Detalhes bibliográficos
Main Authors: Yan, Si, Hou, Guangjin, Schwieters, Charles D., Ahmed, Shubbir, Williams, John C., Polenova, Tatyana
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812427/
https://ncbi.nlm.nih.gov/pubmed/23648839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.027
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