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Internal Dynamics of Dynactin CAP-Gly Is Regulated by Microtubules and Plus End Tracking Protein EB1

CAP-Gly domain of dynactin, a microtubule-associated activator of dynein motor, participates in multiple cellular processes, and its point mutations are associated with neurodegenerative diseases. Recently, we have demonstrated that conformational plasticity is an intrinsic property of CAP-Gly. To u...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yan, Si, Zhang, Huilan, Hou, Guangjin, Ahmed, Shubbir, Williams, John C., Polenova, Tatyana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340406/
https://ncbi.nlm.nih.gov/pubmed/25451937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603118
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