Internal Dynamics of Dynactin CAP-Gly Is Regulated by Microtubules and Plus End Tracking Protein EB1

CAP-Gly domain of dynactin, a microtubule-associated activator of dynein motor, participates in multiple cellular processes, and its point mutations are associated with neurodegenerative diseases. Recently, we have demonstrated that conformational plasticity is an intrinsic property of CAP-Gly. To u...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Yan, Si, Zhang, Huilan, Hou, Guangjin, Ahmed, Shubbir, Williams, John C., Polenova, Tatyana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Molecular Biophysics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340406/
https://ncbi.nlm.nih.gov/pubmed/25451937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603118
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