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An HPLC-tandem mass spectrometry method for simultaneous detection of alkylated base excision repair products
DNA glycosylases excise a broad spectrum of alkylated, oxidized, and deaminated nucleobases from DNA as the initial step in base excision repair. Substrate specificity and base excision activity are typically characterized by monitoring the release of modified nucleobases either from a genomic DNA s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812247/ https://ncbi.nlm.nih.gov/pubmed/23876937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.07.020 |
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