Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer

SLC5A8 is a putative tumor suppressor that is inactivated in more than 10 different types of cancer, but neither the oncogenic signaling responsible for SLC5A8 inactivation nor the functional relevance of SLC5A8 loss to tumor growth has been elucidated. Here, we identify oncogenic HRAS (HRAS(G12V))...

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Huvudupphovsmän: Elangovan, Selvakumar, Pathania, Rajneesh, Ramachandran, Sabarish, Ananth, Sudha, Padia, Ravi N., Srinivas, Sonne R., Babu, Ellappan, Hawthorn, Lesleyann, Schoenlein, Patricia V., Boettger, Thomas, Smith, Sylvia B., Prasad, Puttur D., Ganapathy, Vadivel, Thangaraju, Muthusamy
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811868/
https://ncbi.nlm.nih.gov/pubmed/23918800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01702-12
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