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Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer

SLC5A8 is a putative tumor suppressor that is inactivated in more than 10 different types of cancer, but neither the oncogenic signaling responsible for SLC5A8 inactivation nor the functional relevance of SLC5A8 loss to tumor growth has been elucidated. Here, we identify oncogenic HRAS (HRAS(G12V))...

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Bibliografski detalji
Glavni autori: Elangovan, Selvakumar, Pathania, Rajneesh, Ramachandran, Sabarish, Ananth, Sudha, Padia, Ravi N., Srinivas, Sonne R., Babu, Ellappan, Hawthorn, Lesleyann, Schoenlein, Patricia V., Boettger, Thomas, Smith, Sylvia B., Prasad, Puttur D., Ganapathy, Vadivel, Thangaraju, Muthusamy
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811868/
https://ncbi.nlm.nih.gov/pubmed/23918800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01702-12
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