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Combined Stimulation of Toll-Like Receptor 5 and NOD1 Strongly Potentiates Activity of NF-κB, Resulting in Enhanced Innate Immune Reactions and Resistance to Salmonella enterica Serovar Typhimurium Infection

Pathogen recognition receptors (PRRs) are essential components of host innate immune systems that detect specific conserved pathogen-associated molecular patterns (PAMPs) presented by microorganisms. Members of two families of PRRs, transmembrane Toll-like receptors (TLRs 1, 2, 4, 5, and 6) and cyto...

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Detalhes bibliográficos
Main Authors: Tukhvatulin, Amir I., Gitlin, Ilya I., Shcheblyakov, Dmitry V., Artemicheva, Natalia M., Burdelya, Lyudmila G., Shmarov, Maxim M., Naroditsky, Boris S., Gudkov, Andrei V., Gintsburg, Alexander L., Logunov, Denis Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811746/
https://ncbi.nlm.nih.gov/pubmed/23897616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00525-13
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