Smurf1-Mediated Lys29-Linked Nonproteolytic Polyubiquitination of Axin Negatively Regulates Wnt/β-Catenin Signaling

Ubiquitination plays important and diverse roles in modulating protein functions. As a C2-WW-HECT-type ubiquitin ligase, Smad ubiquitination regulatory factor 1 (Smurf1) commonly serves to regulate ubiquitin-dependent protein degradation in a number of signaling pathways. Here, we report a novel fun...

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Autores principales: Fei, Cong, Li, Zhenfei, Li, Chen, Chen, Yuelei, Chen, Zhangcheng, He, Xiaoli, Mao, Li, Wang, Xin, Zeng, Rong, Li, Lin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811687/
https://ncbi.nlm.nih.gov/pubmed/23959799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00418-13
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