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Two DHH Subfamily 1 Proteins in Streptococcus pneumoniae Possess Cyclic Di-AMP Phosphodiesterase Activity and Affect Bacterial Growth and Virulence

Cyclic di-AMP (c-di-AMP) and cyclic di-GMP (c-di-GMP) are signaling molecules that play important roles in bacterial biology and pathogenesis. However, these nucleotides have not been explored in Streptococcus pneumoniae, an important bacterial pathogen. In this study, we characterized the c-di-AMP-...

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Главные авторы: Bai, Yinlan, Yang, Jun, Eisele, Leslie E., Underwood, Adam J., Koestler, Benjamin J., Waters, Christopher M., Metzger, Dennis W., Bai, Guangchun
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811582/
https://ncbi.nlm.nih.gov/pubmed/24013631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00769-13
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