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Two DHH Subfamily 1 Proteins in Streptococcus pneumoniae Possess Cyclic Di-AMP Phosphodiesterase Activity and Affect Bacterial Growth and Virulence

Cyclic di-AMP (c-di-AMP) and cyclic di-GMP (c-di-GMP) are signaling molecules that play important roles in bacterial biology and pathogenesis. However, these nucleotides have not been explored in Streptococcus pneumoniae, an important bacterial pathogen. In this study, we characterized the c-di-AMP-...

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Bibliografiske detaljer
Main Authors: Bai, Yinlan, Yang, Jun, Eisele, Leslie E., Underwood, Adam J., Koestler, Benjamin J., Waters, Christopher M., Metzger, Dennis W., Bai, Guangchun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811582/
https://ncbi.nlm.nih.gov/pubmed/24013631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00769-13
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