Two DHH Subfamily 1 Proteins in Streptococcus pneumoniae Possess Cyclic Di-AMP Phosphodiesterase Activity and Affect Bacterial Growth and Virulence

Cyclic di-AMP (c-di-AMP) and cyclic di-GMP (c-di-GMP) are signaling molecules that play important roles in bacterial biology and pathogenesis. However, these nucleotides have not been explored in Streptococcus pneumoniae, an important bacterial pathogen. In this study, we characterized the c-di-AMP-...

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Detalhes bibliográficos
Main Authors: Bai, Yinlan, Yang, Jun, Eisele, Leslie E., Underwood, Adam J., Koestler, Benjamin J., Waters, Christopher M., Metzger, Dennis W., Bai, Guangchun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811582/
https://ncbi.nlm.nih.gov/pubmed/24013631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00769-13
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