Population Pharmacokinetics Study of Recommended Zidovudine Doses in HIV-1-Infected Children

The aims of this study were to describe the pharmacokinetics of zidovudine (ZDV) and its biotransformation to its metabolite, 3*-azido-3*-deoxy-5*-glucuronylthymidine (G-ZDV), in HIV-infected children, to identify factors that influence the pharmacokinetics of ZDV, and to compare and evaluate the do...

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Main Authors: Fauchet, Floris, Treluyer, Jean-Marc, Frange, Pierre, Urien, Saik, Foissac, Frantz, Bouazza, Naim, Benaboud, Sihem, Blanche, Stephane, Hirt, Déborah
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811467/
https://ncbi.nlm.nih.gov/pubmed/23877688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00911-13
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