Determination of optimal vitamin D(3) dosing regimens in HIV-infected paediatric patients using a population pharmacokinetic approach

AIMS: To investigate 25-hydroxycholecalciferol [25(OH)D] population pharmacokinetics in children and adolescents, to establish factors that influence 25(OH)D pharmacokinetics and to assess different vitamin D(3) dosing schemes to reach sufficient 25(OH)D concentrations (>30 ng ml(−1)). METHODS: T...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Foissac, Frantz, Meyzer, Candice, Frange, Pierre, Chappuy, Hélène, Benaboud, Sihem, Bouazza, Naïm, Friedlander, Gérard, Souberbielle, Jean-Claude, Urien, Saïk, Blanche, Stéphane, Tréluyer, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Paediatric Clinical Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243886/
https://ncbi.nlm.nih.gov/pubmed/24902982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12433
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