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Rilpivirine Inhibits Drug Transporters ABCB1, SLC22A1, and SLC22A2 In Vitro

Rilpivirine is a nonnucleoside reverse transcriptase inhibitor approved for treatment of HIV-1 infection in antiretroviral-naive adult patients. Potential interactions with drug transporters have not been fully investigated. Transport by and inhibition of drug transporters by rilpivirine were analyz...

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Bibliografiske detaljer
Main Authors: Moss, Darren M., Liptrott, Neill J., Curley, Paul, Siccardi, Marco, Back, David J., Owen, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811300/
https://ncbi.nlm.nih.gov/pubmed/24002095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01421-13
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