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ROCK1 and ROCK2 are Required for Non-Small Cell Lung Cancer Anchorage-Independent Growth and Invasion

Evidence is emerging that the closely related ROCK1 and ROCK2 serine/threonine kinases support the invasive and metastatic growth of a spectrum of human cancer types. Therefore, inhibitors of ROCK are under preclinical development. However, a key step in their development involves the identification...

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Detalhes bibliográficos
Main Authors: Vigil, Dominico, Kim, Tai Young, Plachco, Ana, Garton, Andrew J., Castaldo, Linda, Pachter, Jonathan A., Dong, Hanqing, Chen, Xin, Tokar, Brianna, Campbell, Sharon L., Der, Channing J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810962/
https://ncbi.nlm.nih.gov/pubmed/22942252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2373
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