IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts

Igf2 mRNA binding protein 1 (IMP1, CRD-BP, ZBP-1) is a messenger RNA binding protein that we have shown previously to regulate colorectal cancer (CRC) cell growth in vitro. Furthermore, increased IMP1 expression correlates with enhanced metastasis and poor prognosis in CRC patients. In the current s...

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Bibliografiske detaljer
Main Authors: Hamilton, Kathryn E., Noubissi, Felicite K., Katti, Prateek S., Hahn, Christopher M., Davey, Sonya R., Lundsmith, Emma T., Klein-Szanto, Andres J., Rhim, Andrew D., Spiegelman, Vladimir S., Rustgi, Anil K.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
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Original Manuscript
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810836/
https://ncbi.nlm.nih.gov/pubmed/23764754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt217
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