IMP1 3′ UTR shortening enhances metastatic burden in colorectal cancer

The RNA-binding protein insulin-like growth factor 2 mRNA binding protein 1 (IMP1) is overexpressed in colorectal cancer (CRC); however, evidence for a direct role for IMP1 in CRC metastasis is lacking. IMP1 is regulated by let-7 microRNA, which binds in the 3′ untranslated region (UTR) of the trans...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Andres, Sarah F, Williams, Kathy N, Plesset, Jacqueline B, Headd, Jeffrey J, Mizuno, Rei, Chatterji, Priya, Lento, Ashley A, Klein-Szanto, Andres J, Mick, Rosemarie, Hamilton, Kathryn E, Rustgi, Anil K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556707/
https://ncbi.nlm.nih.gov/pubmed/30407516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy153
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