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EMT and dissemination precede pancreatic tumor formation

Metastasis is the leading cause of cancer-associated death but has been difficult to study because it involves a series of rare, stochastic events. To capture these events, we developed a sensitive method to tag and track pancreatic epithelial cells in a mouse model of pancreatic cancer. Tagged cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rhim, Andrew D., Mirek, Emily T., Aiello, Nicole M., Maitra, Anirban, Bailey, Jennifer M., McCallister, Florencia, Reichert, Maximilian, Beatty, Gregory L., Rustgi, Anil K., Vonderheide, Robert. H., Leach, Steven D., Stanger, Ben Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266542/
https://ncbi.nlm.nih.gov/pubmed/22265420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.11.025
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