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The working stroke of the myosin II motor in muscle is not tightly coupled to release of orthophosphate from its active site

Skeletal muscle shortens faster against a lower load. This force–velocity relationship is the fundamental determinant of muscle performance in vivo and is due to ATP-driven working strokes of myosin II motors, during their cyclic interactions with the actin filament in each half-sarcomere. Crystallo...

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Detalhes bibliográficos
Main Authors: Caremani, Marco, Melli, Luca, Dolfi, Mario, Lombardi, Vincenzo, Linari, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810818/
https://ncbi.nlm.nih.gov/pubmed/23878374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.257410
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