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Orthovanadate and Orthophosphate Inhibit Muscle Force via Two Different Pathways of the Myosin ATPase Cycle
Measurements of the half-sarcomere stiffness during activation of skinned fibers from rabbit psoas (sarcomere length 2.5 μm, temperature 12°C) indicate that addition of 0.1 mM orthovanadate (Vi) to the solution produces a drop to ∼1/2 in number of force-generating myosin motors, proportional to the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3030264/ https://ncbi.nlm.nih.gov/pubmed/21281581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.12.3723 |
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