Caricamento...

Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications

The substitution of Ser187, a residue located far from the active site of human liver peroxisomal alanine:glyoxylate aminotransferase (AGT), by Phe gives rise to a variant associated with primary hyperoxaluria type I. Unexpectedly, previous studies revealed that the recombinant form of S187F exhibit...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Oppici, Elisa, Fodor, Krisztian, Paiardini, Alessandro, Williams, Chris, Voltattorni, Carla Borri, Wilmanns, Matthias, Cellini, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810726/
https://ncbi.nlm.nih.gov/pubmed/23589421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24300
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !