Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer’s disease transgenic mouse model

Baicalein, a flavonoid isolated from the roots of Scutellaria baicalensis, is known to modulate γ-aminobutyric acid (GABA) type A receptors. Given prior reports demonstrating benefits of GABA(A) modulation for Alzheimer’s disease (AD) treatment, we wished to determine whether this agent might be ben...

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Detalhes bibliográficos
Main Authors: Zhang, She-Qing, Obregon, Demian, Ehrhart, Jared, Deng, Juan, Tian, Jun, Hou, Huayan, Giunta, Brian, Sawmiller, Darrell, Tan, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810722/
https://ncbi.nlm.nih.gov/pubmed/23686791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23244
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