Trafficking of mRNAs containing ALREX-promoting elements through nuclear speckles

In vertebrates, the majority of mRNAs that encode secreted, membrane-bound or mitochondrial proteins contain RNA elements that activate an alternative mRNA nuclear export (ALREX) pathway. Here we demonstrate that mRNAs containing ALREX-promoting elements are trafficked through nuclear speckles. Alth...

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Bibliographic Details
Main Authors: Akef, Abdalla, Zhang, Hui, Masuda, Seiji, Palazzo, Alexander F
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810340/
https://ncbi.nlm.nih.gov/pubmed/23934081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.26052
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