Osthole Mitigates Progressive IgA Nephropathy by Inhibiting Reactive Oxygen Species Generation and NF-κB/NLRP3 Pathway

Renal reactive oxygen species (ROS) and mononuclear leukocyte infiltration are involved in the progressive stage (exacerbation) of IgA nephropathy (IgAN), which is characterized by glomerular proliferation and renal inflammation. The identification of the mechanism responsible for this critical stag...

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Autores principales: Hua, Kuo-Feng, Yang, Shun-Min, Kao, Tzu-Yang, Chang, Jia-Ming, Chen, Hui-Ling, Tsai, Yung-Jen, Chen, Ann, Yang, Sung-Sen, Chao, Louis Kuoping, Ka, Shuk-Man
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810132/
https://ncbi.nlm.nih.gov/pubmed/24204969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077794
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