Osthole Mitigates Progressive IgA Nephropathy by Inhibiting Reactive Oxygen Species Generation and NF-κB/NLRP3 Pathway

Renal reactive oxygen species (ROS) and mononuclear leukocyte infiltration are involved in the progressive stage (exacerbation) of IgA nephropathy (IgAN), which is characterized by glomerular proliferation and renal inflammation. The identification of the mechanism responsible for this critical stag...

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Bibliographic Details
Main Authors: Hua, Kuo-Feng, Yang, Shun-Min, Kao, Tzu-Yang, Chang, Jia-Ming, Chen, Hui-Ling, Tsai, Yung-Jen, Chen, Ann, Yang, Sung-Sen, Chao, Louis Kuoping, Ka, Shuk-Man
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810132/
https://ncbi.nlm.nih.gov/pubmed/24204969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077794
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