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DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner

Cell movement is driven by the coordinated regulation of cytoskeletal reorganization through Rho GTPases downstream of integrin and growth-factor receptor signaling. We have reported that mDia, a target protein of Rho, interacts with Src and DIP. Here we show that DIP binds to p190RhoGAP and Vav2, a...

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Bibliografiske detaljer
Main Authors: Meng, Wenxiang, Numazaki, Mitsuko, Takeuchi, Kumiko, Uchibori, Yoshiari, Ando-Akatsuka, Yuhko, Tominaga, Makoto, Tominaga, Tomoko
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC381003/
https://ncbi.nlm.nih.gov/pubmed/14765113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600095
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