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The regulation of mDia1 by autoinhibition and its release by Rho•GTP

Formins induce the nucleation and polymerisation of unbranched actin filaments via the formin-homology domains 1 and 2. Diaphanous-related formins (Drfs) are regulated by a RhoGTPase-binding domain situated in the amino-terminal (N-terminal) region and a carboxy-terminal Diaphanous-autoregulatory do...

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Detalhes bibliográficos
Main Authors: Lammers, Michael, Rose, Rolf, Scrima, Andrea, Wittinghofer, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356318/
https://ncbi.nlm.nih.gov/pubmed/16292343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600879
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