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Gremlin utilizes canonical and non-canonical TGFβ signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells()

The TGFβ/BMP signaling pathways are involved in glaucomatous damage to the trabecular meshwork (TM) leading to elevated intraocular pressure (IOP), which is a major risk factor for the development and progression of glaucoma. The BMP antagonist gremlin is elevated in glaucomatous TM cells and tissue...

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Détails bibliographiques
Auteurs principaux: Sethi, Anirudh, Wordinger, Robert J., Clark, Abbot F.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809843/
https://ncbi.nlm.nih.gov/pubmed/23748100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2013.05.011
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