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Transforming Growth Factor–β Induces Extracellular Matrix Protein Cross-Linking Lysyl Oxidase (LOX) Genes in Human Trabecular Meshwork Cells

PURPOSE. The profibrotic cytokine TGFβ is associated with glaucoma and plays an important role in the regulation of extracellular matrix metabolism in the trabecular meshwork (TM). The purpose of this study was to determine whether expression of ECM cross-linking LOX genes is regulated by TGFβ in TM...

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Bibliografiske detaljer
Main Authors: Sethi, Anirudh, Mao, Weiming, Wordinger, Robert J., Clark, Abbot F.
Format: Artigo
Sprog:Inglês
Udgivet: Association for Research in Vision and Ophthalmology, Inc. 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176072/
https://ncbi.nlm.nih.gov/pubmed/21546528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7287
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