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The Transcription Factor Foxo1 Controls Central Memory CD8(+) T Cell Responses to Infection

Memory T cells protect hosts from pathogen reinfection, but how these cells emerge from a pool of antigen-experienced T cells is unclear. Here we show that mice lacking the transcription factor Foxo1 in activated CD8(+) T cells had defective secondary, but not primary, responses to Listeria monocyto...

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Detalhes bibliográficos
Main Authors: Kim, Myoungjoo V., Ouyang, Weiming, Liao, Will, Zhang, Michael Q., Li, Ming O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809840/
https://ncbi.nlm.nih.gov/pubmed/23932570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.07.013
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