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The Transcription Factor Foxo1 Controls Central Memory CD8(+) T Cell Responses to Infection
Memory T cells protect hosts from pathogen reinfection, but how these cells emerge from a pool of antigen-experienced T cells is unclear. Here we show that mice lacking the transcription factor Foxo1 in activated CD8(+) T cells had defective secondary, but not primary, responses to Listeria monocyto...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3809840/ https://ncbi.nlm.nih.gov/pubmed/23932570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.07.013 |
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