Novel Foxo1–dependent transcriptional programs control T(reg) cell function

Regulatory T (T(reg)) cells, characterized by expression of the transcription factor forkhead box P3 (Foxp3), maintain immune homeostasis by suppressing self-destructive immune responses(1–4). Foxp3 operates as a late-acting differentiation factor controlling T(reg) cell homeostasis and function(5),...

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Autors principals: Ouyang, Weiming, Liao, Will, Luo, Chong T., Yin, Na, Huse, Morgan, Kim, Myoungjoo V., Peng, Min, Chan, Pamela, Ma, Qian, Mo, Yifan, Meijer, Dies, Zhao, Keji, Rudensky, Alexander Y., Atwal, Gurinder, Zhang, Michael Q., Li, Ming O.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771531/
https://ncbi.nlm.nih.gov/pubmed/23135404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11581
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