PP2A-dependent control of transcriptionally active FOXO3a in CD8(+) central memory lymphocyte survival requires p47(phox)

Forkhead box O3a (FOXO3a) transcription factor is regulated by complex post-translational modifications that allow for transcriptional control of various apoptosis factors including pro-apoptotic Bim. Although it has been shown that kinases phosphorylate FOXO3a in memory T cells, the role of protein...

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Detalhes bibliográficos
Main Authors: Liu, Q, Yi, L, Sadiq-Ali, S, Koontz, S M, Wood, A, Zhu, N, Jackson, S H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434656/
https://ncbi.nlm.nih.gov/pubmed/22914323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.118
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