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Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8(+) T cells
Upon infection with an intracellular pathogen, cytotoxic CD8(+) T cells develop diverse differentiation states characterized by function, localization, longevity, and the capacity for self-renewal. The program of differentiation is determined, in part, by FOXO1, a transcription factor known to integ...
में बचाया:
| में प्रकाशित: | J Exp Med |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The Rockefeller University Press
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789410/ https://ncbi.nlm.nih.gov/pubmed/29282254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170697 |
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