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Regulatory T cells use “Itch” to control asthma
Regulatory T cells (Tregs) control type 2 T helper cell–mediated (Th2-mediated) lung inflammation, but the molecular mechanisms by which Tregs execute this activity remain elusive. In this issue of the JCI, Jin et al. reveal that Itch, a HECT-type E3 ubiquitin ligase in Tregs, plays a specific role...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2013
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3809809/ https://ncbi.nlm.nih.gov/pubmed/24162669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72477 |
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