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Regulatory T cells use “Itch” to control asthma
Regulatory T cells (Tregs) control type 2 T helper cell–mediated (Th2-mediated) lung inflammation, but the molecular mechanisms by which Tregs execute this activity remain elusive. In this issue of the JCI, Jin et al. reveal that Itch, a HECT-type E3 ubiquitin ligase in Tregs, plays a specific role...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3809809/ https://ncbi.nlm.nih.gov/pubmed/24162669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72477 |
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