Developmental and tumoral vascularization is regulated by G protein–coupled receptor kinase 2

Tumor vessel dysfunction is a pivotal event in cancer progression. Using an in vivo neovascularization model, we identified G protein–coupled receptor kinase 2 (GRK2) as a key angiogenesis regulator. An impaired angiogenic response involving immature vessels was observed in mice hemizygous for Grk2...

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Detaylı Bibliyografya
Asıl Yazarlar: Rivas, Verónica, Carmona, Rita, Muñoz-Chápuli, Ramón, Mendiola, Marta, Nogués, Laura, Reglero, Clara, Miguel-Martín, María, García-Escudero, Ramón, Dorn, Gerald W., Hardisson, David, Mayor, Federico, Penela, Petronila
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809778/
https://ncbi.nlm.nih.gov/pubmed/24135140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67333
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