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Multiple Scaffolding Functions of β-Arrestins in the Degradation of G Protein-coupled Receptor Kinase 2

G protein-coupled receptor kinase 2 (GRK2) plays a fundamental role in the regulation of G protein-coupled receptors (GPCRs), and changes in GRK2 expression levels can have an important impact on cell functions. GRK2 is known to be degraded by the proteasome pathway. We have shown previously that β-...

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Autori principali: Nogués, Laura, Salcedo, Alicia, Mayor, Federico, Penela, Petronila
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020723/
https://ncbi.nlm.nih.gov/pubmed/21081496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203406
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