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Multiple Scaffolding Functions of β-Arrestins in the Degradation of G Protein-coupled Receptor Kinase 2

G protein-coupled receptor kinase 2 (GRK2) plays a fundamental role in the regulation of G protein-coupled receptors (GPCRs), and changes in GRK2 expression levels can have an important impact on cell functions. GRK2 is known to be degraded by the proteasome pathway. We have shown previously that β-...

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Detalles Bibliográficos
Main Authors: Nogués, Laura, Salcedo, Alicia, Mayor, Federico, Penela, Petronila
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020723/
https://ncbi.nlm.nih.gov/pubmed/21081496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203406
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