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The kinase-independent, second life of CDK6 in transcription

CDK6 is an oncogenic kinase regulating the cell cycle. In this issue of Cancer Cell, Kollmann and colleagues demonstrate that CDK6 performs kinase-independent transcriptional function in regulating expression of VEGF-A and p16(INK4a). These observations link the cell cycle machinery and angiogenesis...

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Sonraí Bibleagrafaíochta
Main Authors: Otto, Tobias, Sicinski, Piotr
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809765/
https://ncbi.nlm.nih.gov/pubmed/23948293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.07.019
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