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Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control
The binding of eIF2–GTP–tRNA(i)(Met) ternary complex (TC) to 40S subunits is impaired in yeast prt1-1 (eIF3b) mutant extracts, but evidence is lacking that TC recruitment is a critical function of eIF3 in vivo. If TC binding was rate-limiting in prt1-1 cells, overexpressing TC should suppress the te...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC380973/ https://ncbi.nlm.nih.gov/pubmed/14976554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600116 |
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